Activation of the Nrf2/Keap1 signaling pathway mediates the neuroprotective effect of Perillyl alcohol against cerebral hypoxic-ischemic damage in neonatal rats

Neonatal hypoxic-ischemic encephalopathy (HIE) is a severe disease with a Louisiana poor prognosis, whose clinical treatment is still limited to therapeutic hypothermia with limited efficacy.Perillyl alcohol (POH), a natural monoterpene found in various plant essential oils, has shown neuroprotective properties, though its effects on HIE are not we

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SOUTH AFRICA AT WAR, 1912-1982

The end of Sprays and Aeresol the Second Anglo-Boer War also put an end to the commando system that had been the core of military strength in South Africa.With the formation of the Union in 1910 it was realized that South Africa will have to provide its own defence.It was to be no easy task; seeing that the English and Afrikaans-speaking VALERIAN R

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